Locomotive Syndrome (LS) is a prevalent condition among older adults. It significantly impacts the quality of life and increases the risk of falls, fractures, and functional decline. This study aimed to compare the effectiveness of two exercise programs, Vivifrail and Locotra, on improving walking speed in elderly individuals with LS. Thirty elderly women aged 65 and older from the Ranginkamanesepid Day Care Center in Isfahan, Iran, participated in this randomized controlled trial, divided into two groups for an eight-week intervention, conducted three times a week. The primary outcome was the 6-meter walking time test, measured before and after the intervention. Both exercise programs demonstrated improvements in walking speed post-intervention; however, no statistically significant difference was found between the two groups. The Vivifrail group had a mean walking time post-test, while the Locotra group also showed improvement. The effect sizes indicated that both programs were effective but did not significantly outperform each other. Both Vivifrail and Locotra exercise programs are beneficial for enhancing walking speed in elderly individuals with LS, and given the lack of significant differences between the two interventions, healthcare providers may consider either program as a viable option for improving mobility in this population.